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PI3K AKT mTOR signalling pathway

Showing 1 - 25 of 4,145
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Bile Acids in Acute Insulin Resistance

Recruiting
  • PI3K Gene Mutation
  • +4 more
  • Drug-induced acute insulin resistance due to PI3K inhibitor, AKT inhibitor, or mTOR inhibitor
  • New York, New York
    Columbia University Medical Center
Oct 6, 2022

Triple Negative Breast Cancer, Metastatic Breast Cancer, Mutation Trial in Shanghai (Everolimus, Investigator's Choice of

Not yet recruiting
  • Triple Negative Breast Cancer
  • +2 more
  • Shanghai, Shanghai, China
    Fudan University Shanghai Cancer Center
Jul 25, 2023

Everolimus-containing Chemotherapy in HER2- mBC PI3K/AKT/mTOR

Completed
  • Breast Cancer
  • +2 more
  • No intervention, it was a retrospective study.
  • Hangzhou, Zhejiang, China
    Zhejiang Cancer Hospital
Sep 13, 2021

Lung Cancer Squamous Cell, Solid Tumors, Head & Neck Cancer Trial in Boston (Palbociclib, Gedatolisib)

Recruiting
  • Lung Cancer Squamous Cell
  • +3 more
  • Boston, Massachusetts
  • +2 more
Jan 9, 2023

Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer Trial in Miami (AI+CDK4/6i, SERD+CDK4/6i, mTOR inhibitor +

Not yet recruiting
  • Breast Cancer
  • +3 more
  • Miami, Florida
    University of Miami
Apr 12, 2023

Breast Cancer Trial in Beijing (Inetetamab, Rapamycin, Pyrotinib)

Not yet recruiting
  • Breast Cancer
  • Beijing, China
    National Cancer Center/National Clinical Research Center for Can
Jan 31, 2021

Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorders Trial (ARQ 092)

No longer available
  • Proteus Syndrome
  • +2 more
  • ARQ 092
  • (no location specified)
Jul 31, 2021

PIK3CA Mutation-Related Tumors Trial in Shanghai (WX390)

Completed
  • PIK3CA Mutation-Related Tumors
  • Shanghai, Shanghai, China
    Shanghai East Hospital
Nov 9, 2023

Solid Tumor, Adult Trial in Seoul (TAS-117)

Completed
  • Solid Tumor, Adult
  • Seoul, Korea, Republic of
    Severance Hospital, Yonsei University Health System
Apr 21, 2021

Low Grade Glioma, World Health Organization (WHO) Grade II Astrocytomas, Oligodendrogliomas Trial in San Francisco (Everolimus,

Terminated
  • Low Grade Glioma
  • +3 more
  • San Francisco, California
    University of California, San Francisco
Nov 3, 2021

HNSCC Trial in Houston (Bimiralisib)

Terminated
Has Results
  • HNSCC
  • Houston, Texas
    M.D. Anderson Cancer Center
Dec 22, 2021

High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma Trial in Worldwide (Ribociclib, Everolimus)

Not yet recruiting
  • High Grade Glioma
  • +8 more
  • Aurora, Colorado
  • +17 more
May 2, 2023

Slow-Flow Vascular Malformation, Fast-Flow Vascular Malformation, Vascular Malformations Trial in Parkville (Alpelisib,

Not yet recruiting
  • Slow-Flow Vascular Malformation
  • +17 more
  • Parkville, Victoria, Australia
    The Royal Children's Hospital
Aug 7, 2023

Breast Cancer Trial in Los Angeles, Bronx (Gedatolisib, Faslodex, Palbociclib)

Active, not recruiting
  • Breast Cancer
  • Los Angeles, California
  • +1 more
Jan 25, 2022

Glioblastoma, Adult Trial in United States (Paxalisib (GDC-0084))

Active, not recruiting
  • Glioblastoma, Adult
  • Paxalisib (GDC-0084)
  • Los Angeles, California
  • +5 more
Aug 16, 2022

Advanced Gastric Adenocarcinoma Trial in Seoul (GSK2636771, Paclitaxel)

Completed
  • Advanced Gastric Adenocarcinoma
  • Seoul, Korea, Republic of
    Severance Hospital, Yonsei University Health System, Yonsei Canc
Apr 21, 2021

Aging Trial (Sirolimus)

Not yet recruiting
  • Aging
  • (no location specified)
Nov 3, 2022

Brain Metastases, Leptomeningeal Metastasis Trial in United States (GDC-0084, whole brain radiation therapy radiation)

Recruiting
  • Brain Metastases
  • Leptomeningeal Metastasis
  • GDC-0084
  • whole brain radiation therapy radiation
  • Miami, Florida
  • +9 more
Jan 3, 2023

Soft-tissue Sarcoma Trial in Philadelphia (TAK-228)

Terminated
Has Results
  • Soft-tissue Sarcoma
  • Philadelphia, Pennsylvania
    Fox Chase Cancer Center
Sep 19, 2022

Patients With PIK3CA-Related Overgrowth Spectrum (PROS)

Not yet recruiting
  • PIK3CA-related Overgrowth Spectrum
  • +8 more
  • national registry
  • Paris, France
    Translational medicine and Targeted therapies unit, Hôpital Neck
Sep 28, 2022

Gallbladder Cancer Trial in Varanasi (Next generation sequencing)

Recruiting
  • Gallbladder Cancer
  • Next generation sequencing
  • Varanasi, UP, India
    Banaras Hindu University
Jun 2, 2022

Postoperative Analgesia, Hand Strength, Health Related Quality of Life Trial (Diclofenac Sodium, Levobupivacaine bolus

Completed
  • Postoperative Analgesia
  • +6 more
  • Diclofenac Sodium
  • +2 more
  • (no location specified)
Apr 26, 2023

Metastatic Breast Cancer, Hormone Receptor Positive Trial in United States (Palbociclib, Tamoxifen, Fulvestrant)

Completed
Has Results
  • Metastatic Breast Cancer
  • Hormone Receptor Positive
  • San Francisco, California
  • +8 more
Feb 16, 2022

Tumor Trial in Worldwide (PF-05212384 (gedatolisib), Docetaxel, Cisplatin)

Completed
Has Results
  • Neoplasm
  • PF-05212384 (gedatolisib)
  • +3 more
  • Birmingham, Alabama
  • +28 more
Sep 9, 2021

Recurrent Endometrial Cancer Trial in France (Olaparib, metformin, metronomic cyclophosphamide)

Completed
  • Recurrent Endometrial Cancer
  • Caen, France
  • +5 more
Dec 6, 2021